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Fas-mediated apoptosis contributes to ventricular remodeling and reduced contractility

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In addition, studies have shown that free radicals in the body can lead to oxidative stress, which has been identified as a precursor for cancer

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This competition for glutathione may potentially result in one of two scenarios: Skeletal muscle may become deprived of enough glutathione to sustain a normal aerobic metabolism during intense or endurance exercise Glutathione depletion may result in a brief immune suppression following the period of intense exercise